Welcome to the Determining Optimal post-Stroke Exercise (DOSE) Home Page!

The DOSE randomized controlled trial is registered on  Please click here to view.


Papers published from the DOSE study:

Protocol paper for the DOSE study:
Klassen TD, Dukelow SP, Bayley MT, Benavente O, Hill MD, Krassioukov A, Liu-Ambrose T, Pooyania S, Poulin MJ, Yao J, Eng JJ. Determining optimal poststroke exercise: Study protocol for a randomized controlled trial investigating therapeutic intensity and dose on functional recovery during stroke inpatient rehabilitation. Int J Stroke. 2018 Jan 1:1747493018785064. doi: 10.1177/1747493018785064.  (View abstract)

This study explored the DOSE therapists’ perceptions of providing the DOSE study intervention to the participants:
Connell LA, Klassen TK, Janssen J, Thetford C, Eng JJ. Delivering Intensive Rehabilitation in Stroke: Factors Influencing Implementation. Phys Ther. 2018 Apr 1;98(4):243-250. doi: 10.1093/ptj/pzy018. (View abstract)

This study examined the validity of the Fitbit One compared to the “gold standard” StepWatch Activity Monitor for assessing patients’ step count during their physical therapy sessions while in stroke inpatient rehabilitation:
Klassen TD, Semrau JA, Dukelow SP, Bayley MT, Hill MD, Eng JJ. Consumer-Based Physical Activity Monitor as a Practical Way to Measure Walking Intensity During Inpatient Stroke Rehabilitation. Stroke. 2017 Sep;48(9):2614-2617. doi: 10.1161/STROKEAHA.117.018175. (View abstract)